Epler Parke is located at the southeast corner of East Street (US 31) and Epler Avenue, just 1 mile south of I-465. Epler Parke is home to IU Heath offices, Epler Parke Dentistry, Walgreens, and several other office and retail users that benefit from the proximity to the Interstate, Greenwood, Downtown Indianapolis, and the dense population of Southport on the south side of Indianapolis.